Article ID Journal Published Year Pages File Type
5222867 Tetrahedron 2011 6 Pages PDF
Abstract

A simple and novel method to the synthesis of 3-fluoro-4-aryl-2-pyridone from a Michael-adduct of fluoronitroacetate and α,β-unsaturated ketone is reported. With (NH4)2CO3 as the N-source and TsOH as the promoted acid, a series of fluorinated-pyridones was obtained with moderate to good yields.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry