Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222867 | Tetrahedron | 2011 | 6 Pages |
Abstract
A simple and novel method to the synthesis of 3-fluoro-4-aryl-2-pyridone from a Michael-adduct of fluoronitroacetate and α,β-unsaturated ketone is reported. With (NH4)2CO3 as the N-source and TsOH as the promoted acid, a series of fluorinated-pyridones was obtained with moderate to good yields.
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