Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5222975 | Tetrahedron | 2009 | 39 Pages |
Abstract
Graphical abstractThis review is intended to update the most recent developments in asymmetric hetero-Diels-Alder (HDA) reactions of carbonyl compounds, covering the literature from 2000 to 2008. The reactions of unactivated aldehydes, activated aldehydes, activated ketones and the inverse HDA reactions of α,β-unsaturated ketones and α,β-unsaturated aldehydes are successively investigated. This review clearly demonstrates the power of asymmetric HDA reactions of carbonyl compounds for the construction of chiral six-membered oxygen-containing heterocycles, with extensive synthetic applications in natural or unnatural products with a wide range of biological activity.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hélène Pellissier,