Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223065 | Tetrahedron | 2010 | 9 Pages |
Abstract
Treatment of various substituted phenols in the presence of (diacetoxyiodo)benzene promotes the formation of a phenoxenium ion, a very electrophilic species able to react with various nucleophiles leading rapidly to a plethora of different cores present in natural products via several novel oxidative processes. This strategy fits within the concept of ‘aromatic ring umpolung’; in this paper a personal account by our laboratory on this thematic is described.
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