Article ID Journal Published Year Pages File Type
5223065 Tetrahedron 2010 9 Pages PDF
Abstract

Treatment of various substituted phenols in the presence of (diacetoxyiodo)benzene promotes the formation of a phenoxenium ion, a very electrophilic species able to react with various nucleophiles leading rapidly to a plethora of different cores present in natural products via several novel oxidative processes. This strategy fits within the concept of ‘aromatic ring umpolung’; in this paper a personal account by our laboratory on this thematic is described.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry