| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223088 | Tetrahedron | 2010 | 5 Pages |
Abstract
The first total synthesis of peumusolide A (1) has been achieved by combination of regio- and stereo-selective aluminum-mediated hydroiodination to 2-yn-1-ol and enantioselective reduction of 4-en-1-yn-3-one with the chiral oxazaborolidine as the key reactions. This total synthesis has unequivocally established our proposed absolute structure of 1.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Satoru Tamura, Shunsuke Doke, Nobutoshi Murakami,