| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223104 | Tetrahedron | 2009 | 6 Pages |
Abstract
Compound 1 is a low molecular weight thrombin inhibitor developed for treatment of deep vein thrombosis and cardiovascular diseases. We herein report our efforts to develop a robust, efficient and reproducible process suitable for large-scale synthesis of compound 1.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Serge Wilmouth, Christel Bufferne-Perret, Christine Flouzat, Grégoire Humblot, Christiane Ray, Nadine Simbille,