| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223133 | Tetrahedron | 2010 | 5 Pages |
Abstract
The 2-pyridyl residue serves as a protecting group for various carboxylic acids. The protecting group is selectively cleaved under mild conditions via N-methylation of the pyridyl group. During the deprotection process, the various functional groups as well as the other ester moieties remain intact. The N-methylated active esters can be subsequently transformed into amides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
