| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223174 | Tetrahedron | 2009 | 5 Pages |
Abstract
Aldehydes or ketones were reacted with 2-(trimethylsilyl)-1,3-dithiane (1) and the products reduced to the corresponding dithianes using tetrafluoroboric acid and sodium borohydride. These sulfur containing compounds were reacted with bromine trifluoride under mild conditions (1-2 min, 0 °C) with a net result of replacing the carbonyls' oxygen with the desired difluoromethyl moiety.
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Chemistry
Organic Chemistry
Authors
Or Cohen, Youlia Hagooly, Shlomo Rozen,