| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223179 | Tetrahedron | 2009 | 13 Pages |
Abstract
The synthesis of seven peptidomimetics of RGD is presented. The indolizidine building block was obtained by condensation of allylglycine with dimethoxydihydrofuran followed by an intermolecular cyclization. The bicyclic ring was functionalised with a carboxylic acid and a guanidinium appendage. The seven peptidomimetics were evaluated by cell-adhesion assays.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Delphine Halie, Joëlle Pérard-Viret, Sylvie Dufour, Jacques Royer,