Article ID Journal Published Year Pages File Type
5223214 Tetrahedron 2010 14 Pages PDF
Abstract

The synthetic versatility of three chemoenzymatically prepared hydroxypiperidine building blocks has been explored, resulting in a library of enantiopure functionalized piperidines. Key steps involved N-acyliminium ion-mediated CC-bond formation and cross-metathesis reactions, after which full deprotection led to the set of free 3-hydroxypiperidines.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry