| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223278 | Tetrahedron | 2010 | 4 Pages |
Abstract
A facile method for the synthesis of 3-substituted 3H-indol-3-ols has been developed. Thus, 2-isocyanophenyl ketones are allowed to react with various Grignard reagents to give the corresponding desired indolol derivatives in generally fair to good yields. The formation of 3-aryl-2,3-dimethylindolin-3-ols by the reaction of 2-isocyanobenzophenones with 2Â M amounts of methylmagnesium bromide is also reported.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kazuhiro Kobayashi, Yuta Okamura, Shuhei Fukamachi, Hisatoshi Konishi,