Article ID Journal Published Year Pages File Type
5223292 Tetrahedron 2010 9 Pages PDF
Abstract

The arylation of thiazoles in 4- and 5-position was investigated in detail. Suzuki–Miyaura and Stille cross-coupling reactions were tested using thiazoles either as halide or organometal species. The obtained results were critically compared to develop helpful guidelines for selection of the cross-coupling methodology with the best potential for good and reliable results for a given synthetic problem without the need for tedious optimization of reaction parameters.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry