Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223292 | Tetrahedron | 2010 | 9 Pages |
Abstract
The arylation of thiazoles in 4- and 5-position was investigated in detail. Suzuki–Miyaura and Stille cross-coupling reactions were tested using thiazoles either as halide or organometal species. The obtained results were critically compared to develop helpful guidelines for selection of the cross-coupling methodology with the best potential for good and reliable results for a given synthetic problem without the need for tedious optimization of reaction parameters.
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