Article ID Journal Published Year Pages File Type
5223352 Tetrahedron 2009 4 Pages PDF
Abstract

Two novel compounds, 3-(hydroxymethyl)-4-methylfuran-2(5H)-one (1) and (3R,4S,1′R)-3-(1′-hydroxyethyl)-4-methyldihydrofuran-2(3H)-one (2), were isolated along with two known ones (3 and 4) from an edible mushroom Mycoleptodonoides aitchisonii. The structures of 1–4 were determined by the interpretation of spectroscopic data. Compounds 1–4 showed protective activity against endoplasmic reticulum (ER) stress-dependent cell death.

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Physical Sciences and Engineering Chemistry Organic Chemistry