Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223380 | Tetrahedron | 2009 | 9 Pages |
Abstract
A study on the reaction mechanism for the conversion of title esters, the species recognised as toxic biomarkers of the oil batches responsible for the Toxic Oil Syndrome, into the corresponding anilides under the thermal conditions of an oil deodorisation process was performed using experimental and computational techniques. The results obtained suggest a reaction course that includes two basic steps: an intramolecular process involving the reaction of the amine group of the diester derivative with the secondary ester of the same compound, followed by the attack of an aniline molecule to form the (E)-isomer of an imidic acid, which would finally tautomerise to give the final anilide.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jordi Escabrós, Ramon Crehuet, Angel Messeguer,