Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223389 | Tetrahedron | 2010 | 6 Pages |
Abstract
The efficient and expeditious syntheses of both enantiomers of the amphibian alkaloid cis-225H have been achieved. Utilizing a common cis-2,5-disubstituted pyrrolidine building block derived from (+)-2-tropinone, the enantioselective syntheses have established the absolute configuration of these alkaloids as (+)-(2R,5S) and (−)-(5S,2R).
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