| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223393 | Tetrahedron | 2010 | 7 Pages |
Abstract
The transfer of the metallocarbene derived from N- and O-protected 6-diazo-5-oxo-l-norleucine (DON) catalyzed by metalloporphyrins undergoes dimerization, cyclopropanation, N-H and S-H insertion reactions, respectively. An efficient and direct synthesis of 5-oxo-l-pipecolic acid from DON is described from unprotected 6-diazo-5-oxo-l-norleucine.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Paul Le Maux, Irène Nicolas, Soizic Chevance, Gérard Simonneaux,