Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223432 | Tetrahedron | 2009 | 7 Pages |
Abstract
A Mannich-type three-component reaction involving aldehydes, acetamide, and enolizable ketones or β-keto esters for the preparation of β-acetamido carbonyl compounds in the presence of TMSCl is described. This newly developed protocol is operationally convenient, widely applicable, and highly diastereoselective.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hui Mao, Jieping Wan, Yuanjiang Pan,