| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223455 | Tetrahedron | 2010 | 6 Pages |
Abstract
DABCO-mediated Morita–Baylis–Hillman reactions of several 1-substituted-indole-2-carboxaldehydes are disclosed. It was discovered that carboethoxy or tert-butoxycarbonyl groups installed at N-1 undergo cleavage under the reaction conditions to afford 2-substituted indoles. Utility of the N-substituted adducts for preparing a variety of annulated indoles has been exemplified.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
