A practical and efficient synthesis of (E)-β-aryl-α,β-unsaturated amides

In this paper, we report a one-step convergent synthesis of (E)-β-monosubstituted α,β-unsaturated amides 3 from α-sulfonyl acetamide 1 and benzyl bromide derivatives 2.

Graphical abstractDownload full-size imageIn this paper, we report a one-step convergent synthesis of (E)-b-aryl a,b-unsaturated amides 3 from a-sulfonyl acetamide 1 and benzyl halide derivatives 2.