| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223544 | Tetrahedron | 2010 | 5 Pages |
Abstract
The reactivity of alkynyl esters tethered to 2-methyl-1,3-cycloalkanediones toward TBAF and TBAF in the presence of 4 Å molecular sieves is reported. Polyfunctionalized diquinanes, allenaotes or oxetanes resulting from anionic domino reactions can be readily available with high to complete diastereoselectivities.
Graphical abstractStarting from alkynyl esters tethered to 2-methyl-1,3-cycloalkanediones, TBAF and TBAF/4 Å molecular sieves promoted diastereoselective domino reactions to afford readily polyfunctionalized diquinanes, allenoates or oxetanes.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
