Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223583 | Tetrahedron | 2008 | 9 Pages |
Abstract
CpCr(CO)3H and HV(CO)4(P-P) (where P-P is a chelating diphosphine) can be used to initiate radical cyclizations by transferring H to activated terminal olefins. CpCr(CO)3H can catalyze reductive cyclizations, with H2 as the ultimate reductant. Appropriate substrates can be assembled by the Morita-Baylis-Hillman reaction of methyl acrylate with an aldehyde. Six- as well as five-membered rings can be formed, and a tandem cyclization to decalin can be effected.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
John Hartung, Mary E. Pulling, Deborah M. Smith, David X. Yang, Jack R. Norton,