| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223590 | Tetrahedron | 2008 | 8 Pages |
Abstract
A new, fluorous-tagged chiral auxiliary has been developed for the asymmetric, SmI2-mediated coupling of aldehydes and α,β-unsaturated esters. γ-Butyrolactones are obtained in moderate to good isolated yield and in high enantiomeric excess. The fluorous tag allows the auxiliary to be conveniently recovered by fluorous solid-phase extraction (FSPE) and reused.
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Related Topics
Physical Sciences and Engineering
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