| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223607 | Tetrahedron | 2010 | 5 Pages |
Abstract
Rongalite® promotes cleavage of diaryl disulfides generating chalcogenolate anions that then undergo facile acylation with anhydrides in the presence of CsF to afford thioesters (3) with good to excellent yields. By using the present protocol, 5-arylthio-5-oxopentanoic acid (4) can be facilely prepared. The important features of the methodology are broad substrate scope, simple operation, and no requirement for metal catalysts. It is noteworthy that acylations of diphenyl diselane with anhydrides are also conducted smoothly to afford selenoesters (5) in good yields under the standard conditions.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Weixing Dan, Hongjuan Deng, Jiuxi Chen, Miaochang Liu, Jinchang Ding, Huayue Wu,