| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223704 | Tetrahedron | 2008 | 9 Pages |
Abstract
Barbier allylation of 5,6-dihydropyrazin-2(1H)-ones leads to a single isomer of 3-allylpiperazin-2-ones in high yields. Further Pictet-Spengler-Grieco cyclization of 3-allylpiperazin-2-ones with aldehydes provides bicyclic and tricyclic piperazinones with high diastereoselectivity.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
A. Viso, R. Fernández de la Pradilla, A. Flores, M.A. del Águila,