Article ID Journal Published Year Pages File Type
5223717 Tetrahedron 2008 6 Pages PDF
Abstract

An efficient copper-free Sonogashira coupling of 2-chloroquinolines with phenyl acetylene to 2-ethynylquinolines is described. We further discussed the one pot facile annulation of 2-alkynylquinoline-3-carboxaldehydes to 3-phenylbenzo[b][1,6]naphthyridines in aqueous ammonia in excellent yield.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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