Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223721 | Tetrahedron | 2008 | 5 Pages |
Abstract
A convenient one-step synthesis of chiral γ-lactones has been performed. The method is based on enantioselective hydrogenation of γ-ketoesters using the RuCl3-BINAP-HCl catalytic system. Chiral γ-lactones (91-99% ee) have been isolated in 57-88% yield.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eugenia V. Starodubtseva, Olga V. Turova, Maxim G. Vinogradov, Lilia S. Gorshkova, Vladimir A. Ferapontov, Marina I. Struchkova,