Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223732 | Tetrahedron | 2008 | 6 Pages |
Abstract
An unprecedented efficient and chemoselective DRA of benzaldehydes and primary amines was developed to directly yield N-monosubstituted benzylamine hydrochlorides as single products in practically quantitative yields. The method was characterized by simply adding a few milliliters of CHCl3 in the conventional Pd-C catalytic hydrogenation system at atmospheric pressure and room temperature. A self-modulated system and a four-stage cyclic pathway were proposed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lixin Xing, Chuanjie Cheng, Rui Zhu, Boyang Zhang, Xinyan Wang, Yuefei Hu,