| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223785 | Tetrahedron | 2010 | 8 Pages |
Abstract
A set of 11 non-symmetric cyclic sulfamide HIV-1 protease inhibitors were synthesized and evaluated. The use of a key microwave-assisted silver(I) oxide mediated selective mono N-benzylation reaction enabled fast and straightforward synthesis. The Ki values of the new inhibitors ranged between 0.28 μM and >20 μM.
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