Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223823 | Tetrahedron | 2010 | 9 Pages |
Abstract
Readily available, low molecular cyclohexane-based organocatalysts promote highly enantioselective desymmetrizations of cyclic meso-anhydrides applying alcohols and benzyl mercaptan as nucleophiles. Both succinic and glutaric anhydrides furnished the corresponding products with up to 96% ee in mostly quantitative yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ellen Schmitt, Ingo Schiffers, Carsten Bolm,