Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5223870 | Tetrahedron | 2010 | 6 Pages |
Abstract
A self-catalytic protocol was developed using an aza-Friedel-Crafts method to generate 1-naphthoyl tetrahydroisoquinoline products under solvent-free conditions or in/on water. Yields were increased with the use of water. The reaction proceeded with 100% atom economy in the absence of any additional catalyst.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Patricia D. MacLeod, Zhiping Li, Chao-Jun Li,