| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223873 | Tetrahedron | 2010 | 6 Pages |
Abstract
The palladium-catalyzed coupling reaction of aryl halides with terminal alkynes, the Sonogashira coupling, took place in water under copper-free conditions by use of an amphiphilic polystyrene-poly(ethylene glycol) (PS-PEG) resin-supported palladium-phosphine complex to give the corresponding aryl-substituted alkynes in high yields. The PS-PEG resin-supported palladium catalyst was recovered by simple filtration and reused four times without any loss of catalytic activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Toshimasa Suzuka, Yukari Okada, Kazumasa Ooshiro, Yasuhiro Uozumi,