| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223933 | Tetrahedron | 2008 | 5 Pages |
Abstract
A diastereoselective cycloaddition of a soluble polymer-supported Baylis–Hillman adduct with nitrile oxides is described. The reaction has shown to proceed with moderate diastereoselectivity, favoring the syn isomer of the resulting 3,5-substituted isoxazolines. The stereochemistry of the products has been assigned using 1H NMR studies. The structure of one of the diastereomers has been determined by single-crystal X-ray crystallographic analysis.
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