| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5223982 | Tetrahedron | 2010 | 4 Pages |
Abstract
A one-pot and highly diastereoselective method for the reductive dehydroxylation of three classes of heterocyclic N,O-acetals with general structure 4 is reported. The method features a 'two in one' concept, namely, by synergetic action of two complementary Lewis acids (BF·OEt2 and TiCl4), the bicyclic or tricyclic oxazololactams 5 were formed in situ and reductively cleaved to give the corresponding lactams 6 in a high-yielding and highly diastereoselective manner.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Li-Jiao Jiang, Bo Teng, Jian-Feng Zheng, Jian-Liang Ye, Pei-Qiang Huang,