Article ID Journal Published Year Pages File Type
5223992 Tetrahedron 2010 9 Pages PDF
Abstract

Tricyclic valerolactams characterized by a variable heteroatom in γ-position, for example, sulfur, oxygen or nitrogen, were synthesized starting from 2,5-dihydrooxazoles. The chosen synthetic procedures included the addition of thiosalicylic acid as well as the addition of salicyl chloride. The nitrogen containing lactams were prepared in a cycloaddition and subsequent oxidation.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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