Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224027 | Tetrahedron | 2010 | 5 Pages |
Abstract
The enantioselective total synthesis of idesolide has been accomplished in 20% overall yield from a known allylic alcohol by a nine-step sequence involving the Sharpless asymmetric epoxidation as the source of chirality and an efficient NaHCO3-promoted dimerization of the monomeric form of idesolide as the key transformation.
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