Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224034 | Tetrahedron | 2010 | 7 Pages |
Abstract
A cheap, versatile and convenient method for synthesis of β-lactams using methoxymethylene-N,N-dimethyliminium salt as an acid activator in Staudinger reaction is reported. This method is used for the preparation of monocyclic, spirocyclic, N-alkyl and three-electron-withdrawing group β-lactams. The products are obtained in good to excellent yields.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry