Article ID Journal Published Year Pages File Type
5224041 Tetrahedron 2010 6 Pages PDF
Abstract

Six new highly oxygenated daphnane-type diterpenoids, trigochinins D–I (1–6), were isolated from the twigs and leaves of Trigonostemon chinensis. Their structures with the absolute configuration were established on the basis of spectroscopic method and CD analysis. Trigochinins D–F (1–3) possessed a rare 4,6-oxetane moiety in this compound class. Trigochinins E and F exhibited significant inhibiting activity against HL-60 tumor cell line.

Graphical abstractSix new highly oxygenated daphnane-type diterpenoids, trigochinins D–I (1–6), were isolated from Trigonostemon chinensis. Their structures with the absolute configuration were determined by spectroscopic method and CD analysis. Trigochinins E and F exhibited inhibition on HL-60 tumor cell line.Figure optionsDownload full-size imageDownload as PowerPoint slide

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Physical Sciences and Engineering Chemistry Organic Chemistry