| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5224089 | Tetrahedron | 2008 | 6 Pages |
Abstract
LTMP (5Â equiv) metalates randomly veratric acid (1). Under external quench conditions, the thermodynamically more stable lithium 2-lithio-3,4-dimethoxybenzoate (2) reacts with a variety of electrophiles to give versatile building units that are not easily accessible by conventional means. Under in situ quench conditions (LTMP/TMSCl), a reversal of regioselectivity is observed and 6-trimethylsilyl-3,4-dimethoxybenzoic acid (10) is formed predominantly.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nguyet Trang Thanh Chau, Thi Huu Nguyen, Anne-Sophie Castanet, Kim Phi Phung Nguyen, Jacques Mortier,