Article ID Journal Published Year Pages File Type
52241 Catalysis Communications 2008 6 Pages PDF
Abstract

A simple, green and cost-effective protocol was achieved for the solvent free synthesis of 1,4-dihydropyridines catalyzed by AlCl3 · 6H2O as a mild and effective catalyst at 60 °C in high yields. 1,4-Dihydropyridines thus formed were aromatized to pyridines by in situ generation of HOCl employing AlCl3 · 6H2O/H2O2/H2O/EtOH as an excellent reagent system under domestic microwave irradiation (MWI). Both the synthesis and oxidation steps were efficiently accomplished in one-pot four-component fashion following the same protocol.

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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