Article ID Journal Published Year Pages File Type
5224126 Tetrahedron 2010 5 Pages PDF
Abstract

A multi-component synthesis of 3-aryl-1-(arylmethylideneamino)pyrrolidine-2,5-diones is described. A mixture of N-isocyaniminotriphenylphosphorane, an aldehyde, and Meldrum's acid undergo a 1:2:1 addition reaction under mild conditions to afford the title compounds in good to excellent yields.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry