| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5224203 | Tetrahedron | 2010 | 6 Pages |
Abstract
Enantioselective synthesis of two anti-tumor antibiotics, (−)-methylenolactocin and (−)-protolichesterinic acid, has been achieved through titanocene(III) chloride mediated radical cyclization reaction starting from commercially available d-mannitol. Titanocene(III) chloride (Cp2TiCl) was prepared in situ from commercially available titanocene dichloride (Cp2TiCl2) and zinc dust in THF.
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