Article ID Journal Published Year Pages File Type
5224240 Tetrahedron 2008 6 Pages PDF
Abstract

A tandem Michael addition/ylide olefination for the rapid creation of highly functionalized cyclohexadiene is developed. The tandem annulation reactions afford versatile cyclohexadienes in good to excellent isolated yields. This method has been successfully applied to the synthesis of three biologically active molecules.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry