Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224242 | Tetrahedron | 2008 | 5 Pages |
Abstract
A mild, efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via a three-component condensation of aldehyde, amine and TMSCN in the presence of a catalytic amount of indium(III) iodide in water. The reactions proceeded smoothly at room temperature in water to generate the corresponding products in moderate to excellent yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhi-Liang Shen, Shun-Jun Ji, Teck-Peng Loh,