Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224371 | Tetrahedron | 2008 | 7 Pages |
Abstract
A two-step conversion of 1,3-disubstituted arenes to chiral α,α-diaryl methylammonium chlorides is described. In this procedure, arenes are converted to aryl boronic esters by iridium-catalyzed borylation, and the aryl boronic esters are converted to enantioenriched amines by subsequent rhodium-catalyzed addition to chiral tert-butanesulfinimes.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Timothy A. Boebel, John F. Hartwig,