Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224391 | Tetrahedron | 2008 | 7 Pages |
Abstract
Several heterocycles such as furanones, pyrrolones, and indolizines, which are of pharmacological importance, are easily accessed via the Pt(II)-catalyzed heterocyclization/1,2-migration of propargylic ketols or hydroxy imine derivatives. This method sidesteps the challenges of traditional heteroaromatic oxygenation strategies such as regioselectivity and functional group tolerance in the syntheses of these heterocycles.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eric M. Bunnelle, Cameron R. Smith, Sharon K. Lee, Surendra W. Singaram, Allison J. Rhodes, Richmond Sarpong,