Article ID Journal Published Year Pages File Type
5224405 Tetrahedron 2009 8 Pages PDF
Abstract

Endoperoxides belonging to the G-factor family, containing a spiroalkane moiety in the α position to the O–O bond, have been synthesized via an autoxidation reaction on the corresponding dienol precursors. Methylated derivatives in the peroxyhemiketal position have also been prepared. The in vitro antimalarial activities are reported. Fe(II)-induced reduction on endoperoxides 8 and 9 have been studied.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry