Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224427 | Tetrahedron | 2009 | 4 Pages |
Abstract
The reaction of 2-(chloromethyl)phenyl isocyanides, readily available by dehydration of the respective N-[2-(chloromethyl)phenyl]formamides, with organolithiums produced 2-substituted indoles in satisfactory yields through addition of organolithiums to the isocyano carbon followed by intramolecular substitution reaction of the resulting imidoyl anion intermediates.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kazuhiro Kobayashi, Daisuke Iitsuka, Shuhei Fukamachi, Hisatoshi Konishi,