| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5224434 | Tetrahedron | 2009 | 7 Pages |
Abstract
Chaetomugilins I-O were isolated from a strain of Chaetomium globosum originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR techniques, as well as chemical transformations. These compounds exhibited significant growth inhibition of cultured P388, HL-60, L1210, and KB cell lines. In addition, chaetomugilin I showed selective cytotoxic activity against 39 human cancer cell lines.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yasuhide Muroga, Takeshi Yamada, Atsushi Numata, Reiko Tanaka,