Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224480 | Tetrahedron | 2008 | 6 Pages |
Abstract
Fluorine-containing esters were demonstrated to be convenient substrates for construction of the corresponding ketones by low temperature reaction with Grignard reagents followed by warming up to 0 °C, while heating the mixture up to 80 °C readily promoted the reduction of the ketones obtained by the generated magnesium alkoxides whose mechanism was speculated as Meerwein-Ponndorf-Verley type reduction by computational technique.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Takashi Yamazaki, Tsukasa Terajima, Tomoko Kawasaki-Taskasuka,