| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5224510 | Tetrahedron | 2010 | 7 Pages |
Abstract
An improved practical protocol for the synthesis of both anomers of 1-ethynyl-2-deoxiribosides 1 was developed. The Sonogashira coupling of ethynyldeoxyribosides 1 with various aryl- and heteroaryl halides was carried out under various conditions. It was found that the use of copper-free coupling protocols could reduce the oxidative dimerisation in favour of arylalkynyldeoxyriboside formation.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
TomáÅ¡ Bobula, Michal Hocek, Martin Kotora,