Article ID Journal Published Year Pages File Type
5224565 Tetrahedron 2008 5 Pages PDF
Abstract

Novel regioisomers of 2′-methyl-branched nucleosides were designed and synthesized to mimic potent anti-viral drugs like Valopicitabine. The short and efficient synthesis of the targets involves a one-pot tosylation/cyclization step that leads to an activated furan scaffold on which the isonucleosides were built.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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