Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5224565 | Tetrahedron | 2008 | 5 Pages |
Abstract
Novel regioisomers of 2â²-methyl-branched nucleosides were designed and synthesized to mimic potent anti-viral drugs like Valopicitabine. The short and efficient synthesis of the targets involves a one-pot tosylation/cyclization step that leads to an activated furan scaffold on which the isonucleosides were built.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tony Bouisset, Gilles Gosselin, Ludovic Griffe, Jean-Christophe Meillon, Richard Storer,